Biography:
Dr. S. Raghunandhakumar currently serves as an Associate professor in this department. In addition, he is taking care of Stem cell bio-bank for regenerative medicine at Saveetha Dental College. Prior to this, he started his research career as a postdoctoral fellow in premier research centres from both national (CCMB-Hyderabad & CBT-Anna University) and international (Israel & USA) platform. He did his Masters and Ph.D at University of Madras. Over all he has more than 11 years of experience in teaching as well as in research field. During this period, he has secured several fellowships, awards and publication from his core research domain.
Education:
Post-Doctoral Training, University Texas, USA
Ph.D. Biochemistry, Madras University
M.Sc. Pharmacology and Toxicology, University of Madras
B.Sc. Botany, Bharathidasan University
Thrust Areas: Stem cell and Regenerative medicine, Immunotherapy, Discovery of Small Molecules for Cancer & Cancer Stem cell therapy, Tissue engineering & 3D Organoid Culture.
Selected Recent Publications:
1. Murugan, S.K., Bethapudi, B., Raghunandhakumar, S., Purusothaman, D., Nithyanantham, M., Mundkinajeddu, D. and Talkad, M.S., 2022. A flavonoid rich standardized extract of Glycyrrhiza glabra protects intestinal epithelial barrier function and regulates the tight-junction proteins expression. BMC complementary medicine and therapies, 22(1), pp.1-14.
2. Packirisamy, V., Raghunandhakumar, S., and Pandurangan, P., 2022. Solvent-driven thiol protected luminescent cobalt nanoclusters. Journal of Molecular Liquids, 354, p.118857. IF: 6.16
3. Ishaniya, W., Sumithaa, C., Raghunandhakumar, S., Vimalraj, S. and Ganeshpandian, M., 2022. Nano-encapsulation of melatonin into polydiacetylene-phospholipid assembly for sustained-release and enhanced bone formation in zebrafish. Journal of Drug Delivery Science and Technology, p.103415. IF: 3.98
4. Jothipandiyan, S., Devarajan, S., Sekaran, S., Sudharsan, M., Raghunandhakumar, S and Paramasivam, N., 2022. Transition metal complex laminated bioactive implant alleviates Methicillin Resistant Staphylococcus aureus virulence. Biomaterials Advances, p.212813. IF: 7.32
5. Chandrashekar, N., Subramanian, R. and Thiruvengadam, D., 2022. Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo (a) pyrene‐induced pulmonary carcinogenesis in mice. Journal of Biochemical and Molecular Toxicology, p.e23053. IF: 3.65
6. Elumalai P, Ezhilarasan D, Raghunandhakumar S. Quercetin Inhibits the Epithelial to Mesenchymal Transition through Suppressing Akt Mediated Nuclear Translocation of β-Catenin in Lung Cancer Cell Line. Nutr Cancer. 2021 Aug 2:1-13. doi: 10.1080/01635581.2021.1957487. Epub ahead of print. PMID: 34338101.
7. S. Angamuthu, ChidambaramR. R. S.Thangaswamy, Deepa Rani .S, Veeraiyan DeepakNallaswamy, Raghunandhakumar Subramanian, Raja Ganesan, Amutha Raju; Metabolic annotation, interactions and characterization of natural products of mango (Mangifera indica L.): 1H NMR based chemical metabolomics profiling; Vol. 108, Sep. 2021,18-25.
8. Vimalraj Selvaraj, Raghunandhakumar Subramanian ,Sekaran Saravanan, Deepak Nallaswamy Veeraiyan and Lakshmi Thangavelu ,Process Biochemistry,Ferulic acid-Cu(II) and Zn(II) complexes promote bone formation,(2021)pg.no-141-152.
9. Ezhilarasan D, Lakshmi T, Subha M, Deepak Nallasamy V, Raghunandhakumar S. The ambiguous role of sirtuins in head and neck squamous cell carcinoma. Oral Dis. 2021 Feb 11. doi: 10.1111/odi.13798. Epub ahead of print. PMID: 33570800.
10. Vimalraj S, Subramanian R, Saravanan S, Arumugam B, Anuradha D. MicroRNA-432-5p regulates sprouting and intussusceptive angiogenesis in osteosarcoma microenvironment by targeting PDGFB. Lab Invest. 2021 Aug;101(8):1011-1025. doi: 10.1038/s41374-021-00589-3. Epub 2021 Apr 12. PMID: 33846539.